ABSTRACT
Background: India is an agrarian country, where pesticides are most widely used in farming. Monsoon dependent agricultural practices are common in India. In present study socioeconomic class and prescribing pattern of commonly used drugs in organophosphate poisoning in indoor setting at tertiary care hospital is evaluated. The aim of the study was to evaluate prescribing trend of drugs and socioeconomic class of patients in organophosphate poisoning in monsoon season.Methods: Prospective observational study was conducted at Medical Intensive Care Unit (MICU) and Medicine Wards for 4 months at 540 bedded tertiary care teaching hospital.Results: Total 64 diagnosed cases were enrolled and analyzed in present study (n=64). Maximum number of cases (57.81%) were male followed by female (42.18%). Most of the cases (37.50%) were from the age group of 21-30 years. 49 (76.56%) patients were of primary intentional poisoning followed by 15 (23.43%) patients of accidental poisoning. Most common drugs prescribed were atropine, pralidoxime, cefotaxime and ranitidine. The average amount of atropine and pralidoxime used per patient/day were 37.89±63.63 mg and 10.07±26.87 gm respectively.Conclusions: Present study revealed that young male adults with low socioeconomic class from rural background were prone for intentional organophosphate poisoning in central India.
ABSTRACT
Background: To analyze the prescribing patterns of statins a hypolipidemic agents by using HMIS database in outdoor patients at tertiary care teaching hospital of central India.Methods: In this retrospective study Using HMIS database, 1000 prescriptions were analyzed for statin use for various WHO prescription indicators using ATC code of statins, the ratio of prescribed daily dose (PDD) and defined daily dose (DDD) was calculated.Results: Atorvastatin was the only statin which was prescribed as monotherapy (61.1%), whereas as combination with aspirin (38.9%). While analyzing the prescriptions, it was found that patients having abnormal lipid profiles (51.8%) and normal lipid profiles (48.2%) were prescribed atorvastatin. Hypertension with diabetes (37%) was the most common disease followed by hypertension (21.2%) and diabetes mellitus (21%) for which atorvastatin was prescribed. The average number of drugs per prescription were 3.8±1.65.Conclusions: This study depicts the use of atorvastatin in various disease conditions, both as primary and secondary preventive measures. There was no polypharmacy. Such studies should be done to educate the physicians on good prescribing practices and to rationalize use of hypolipidemic drugs.